Growth Hormone Secretagogues, also called GHSs, are synthetic chemicals, both in the form of peptides and non-peptides (research chemicals), that stimulate Growth Hormone release.
To truly understand what this means, first let’s break apart this by each term.
What is Growth Hormone?
Growth Hormone (GH), also known as somatotropin or Human Growth Hormone (HGH) in humans, is a peptide hormone that stimulates cell reproduction, growth and regeneration in humans and animals.
Growth hormone production naturally decreases with age which has recently made it a popular medical treatment prescribed by doctors for growth hormone deficiency in adults to increase vitality.
What is a secretagogue?
A Secretagogue is a chemical or peptide that causes another chemical or hormone to be secreted.
What is an agonist?
An agonist is a chemical or peptide that binds to a specific receptor and therefor activates the receptor to produce, or secrete, a chemical or hormone or a similar action. Alternatively, an antagonist causes the opposite effect of an agonist. For example, if an agonist causes the receptor to product more Growth Hormone, then an antagonist would cause the receptor to product less, or block the production of growth hormone.
Now that we understand these terms, let’s take another look at Growth Hormone Secretagogues (GHSs).
What are Growth Hormone Releasing Secretagogues (GHSs)
Growth Hormone Secretagogues (GHSs) are drugs, peptides or research chemicals, which induce the secretion of GH (growth hormone). They include agonists of both the Growth Hormone Secretagogue Receptor (GHSR) such as GHRP-2, GHRP-6, Hexarelin and Ipamorelin which are all peptides and MK-677 which is a research chemical as well as agonists of the Growth Hormone Releasing Hormone Receptor (GHRHR) such as Sermorelin, Tesamorelin and CJC 1295 which are all peptides. These agonist peptides also induce the secretion of IGF-1 and other hormones like prolactin and cortisol. IGF-1 (Insulin -like Growth Factor 1) is a protein that regulates the concentration of free fatty acids and glucose. You can buy peptides online and find igf-1 lr3 for sale at Top Peptides.
Growth Hormone Releasing Hormone Receptors
The GHRHR (Growth-hormone-releasing hormone receptor) is a G-protein-coupled receptor which binds growth hormone-releasing hormones together. It activates a Gs protein which causes intracellular signaling molecules called cAMPs via Adenylate cyclase pathways.
The function of this receptor is to release Growth Hormone. Binding to the receptor leads to the release of additional growth hormone.
GHRHR Peptides
• CJC-1295 DAC
• Dumorelin
• GHRH (somatorelin)
• Rismorelin
• Sermorelin
• Tesamorelin
Growth hormone secretagogue receptors
Growth hormone secretagogue receptor(GHS-R) is also known as the ghrelin (the “hunger hormone” receptor. It is a G protein-coupled receptor which binds growth hormone secretagogues (GHSs). The role of GHS-R is regulating both body weight and energy homeostasis. Thiscombination has also made is a potential for abuse as a performance enhancing drug.
The function of GHS-R’s is to release growth hormone by binding to the GHS-R1a which is located in the pituitary cells and stimulating the pituitary gland’s growth hormone (GH) secretion.
Ghrelin (GHS) receptor agonist Peptides
• Alexamorelin
• Hexarelin
• Ghrelin (GHRL)
• GHRP-1
• GHRP-2
• GHRP-3
• GHRP-4
• GHRP-5
• GHRP-6
• Ipamorelin
Ghrelin (GHS) receptor agonist non-peptides (research chemicals)
• Adenosine
• Anamorelin
• Capromorelin
• Ibutamoren
• SM-130686
Where to buy Growth Hormone Releasing Secretagogue (GHS) Peptides
You can buy peptides and research chemicals online on research peptide websites for research purposes and never for human consumption. I recommend Top Peptides. They have a huge selection and great prices. You can buy GHRP 6or any other Peptides for Sale there.
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