Tuesday, March 19, 2019

Peptides for Sale Online: A Review of 4 of the best Peptide Companies

Buying peptides online can be very difficult.  There are hundreds of peptide manufacturers online to choose from.  Which company can you trust? 
Here’s a review of the top4USA peptides companies that have Peptides for Sale on their websites that we have personally tried over the last 10 years. Scores were given from 1-10 with 1 being bad, 5 being average and 10 being the best. 
Not everyone we researched made the cut.  There were 12 companies we looked at and attempted to order from and communicate with to gauge product quality, customer support, shipping time and more listed below.  The factors used to consider who to recommend as a trusted online USA peptide supplier were as follows:
•    Inventory Size andSelection.  We found that the number of products offered per peptide online store ranged from around 40 to over 100 with the average number around 60 different research chemicals and peptides.
•    Price.  This is the advertised price. This does not include coupons discounts.
•    Shipping.  Were that packages sent out the next business day and did I receive a tracking email.
•    Packaging.  Did the company use bubble wrap, the proper size box, include and invoice, etc.
•    USA Peptide company.  Verified with each company.
•    Customer service.   Did they respond to general questions about their order within 24 hours and on the weekend?
•    Discounts and Sales.  Do they send out weekly deals and coupons?
•    Quality/Accuracy of the chemicals.  We tested the chemicals to verify their strength and also measured the size.  For example, when it says 30ml, did the company send 28ml or 32ml.
•    Payment Options.  Due to merchant processors classifying peptides as “high risk”, most of these companies don’t take credit cards as payment sources.  There are a few however that do.Companies with credit card processing ON THEIR SITE received a 10 which none had due to the lack of credit card processing available for this industry.
•    Years in business. (over 10 years received a 10, 6-9 received a 9 and 2-5 received a 5.

There were about 5 large peptide companies that I did not include in this review because I could not verify that they were a USA Peptides Company and, in my opinion, I don’t trust companies that won’t respond to you when attempting to verify their legitimacy.  I also did not include companies that scored less than an 80/100 as the goal of this review is to help you find trusted sources online to buy peptides and research chemicals, not to bash a company’s reputation. 
Scores were given on a scale of 1-10 with 1 being the worse, 5 being average and 10 being the best.  Here’s what we found.

1.    Top Peptides www.toppeptides.com

Top Peptides sells high quality peptides at some of the lowest prices on the internet.  They’ve been around since 2010. With over 100 research chemicals and peptides to choose from including some hard to find research chemicals likeFlualprazolam, Flubromazolam, Diclazepam and Clonazolam for sale.  This is my number one research chemical supplier. 

Although they did not have credit card processing during the checkout process, the purchase process was very simple.  Once I checked out on their online store, I received an email with an invoice and several different payment optionsoptionsincluding the ability to pay with a credit card along with others like Venmo, Zelle, GPay and evenAmazon gift cards.

I’ve ordered from them several times per year and they’ve always shipped the peptides within 24 hours Monday -Friday and same day by 4pm.  The package was a sealed Small flat rate USPS box which means the products were shipped domestically.  The box was the correct size and the products were bubble wrapped.  A stamped invoice was included in the box and a tracking email was sent to me within 24 hours of purchase.

I tested their research chemicals for purity and accuracy and found that their chemicals and peptides are usually within about 3% accuracy, in most cases on the high side. 

I’ve signed up for their newsletter and they send me an email every Friday with a coupon code for their weekend sale with discounts ranging from 25% to 60% off. 

2.    Imperial Peptides

This company has been around for almost 3 years and are extremely responsive to emails and customer support.  Their selection is above average with over 80 different research chemicals and peptides. 

Their prices are better than the majority of the other companies and combined with an above average weekly coupon ranging from 15%-35%, I found them to be a solid online Peptides supplier.  I’ve ordered several different peptides from their website.  All of their chemicals were overfilled by about 2ml and their peptides were extremely accurate when verified in the laboratory. 

Order are usually shipped the same day and are very professional.  Your invoice will be included in your USPS box and tracking numbers were emailed the next day.

Upon checkout, you’ll receive an invoice with several payment options.  With Imperial Peptides, you don’t have to wait for it to be manually sent which is a huge convenience.  Within seconds, just check your email (also check spam folder) and several different payment options will be in your inbox.  They do have credit card processing available which will be sent on a separate email usually within a few hours after your purchase.  I’ve also found them to be very responsive on the weekends. 

I use them very regularly as they carry 2 research chemicals that from time to time Top Peptides is out of and has lower prices on almost ten of the peptides I order regularly.

3.    Domestic Peptides

Domestic Peptides is a USA based Peptide Manufacturer with above average low pricing, a large selection of almost 90 research chemicals and a very consistent and reliable business. 

I use this company regularly because of its especially larger selection of SARM’s.

They’ve been in business almost 3 years and I’ve found very little wrong with this company except on the weekends, it may take till the next business morning for a reply on customer service issues.  In saying that, aside from testing them for this review, I’ve never actually had any issues with any of the orders I’ve placed.  Solid trustworthy company.

Like the others, the shipping standards are sealed USPS boxes, tamper proof seals around every edge and all products bubble wrapped.  Invoice is included and tracking numbers are provided.  They even offer free shipping on orders over $150.

The quality of their products is excellent and the strength or potency of their research chemicals are usually slightly stronger so you definitely get your monies worth.  Compared to the other, I wish they sent out larger weekly deals and coupons.  The ones I’ve gotten about once a month have been between 10% -25% off.


4.    Enhanced Peptides

Enhanced Peptides scored extremely high in almost every category.  Overall, they are one of my favorite USA Peptide stores online.  I buy peptides and research chemicals from Enhanced Peptides regularly because I find that they have slightly over 90 products to choose from and they are a good store to compare weekly deals with.  In saying that their regular pricing is lower than the majority of the companies online, however slightly higher than places like Top Peptides, Imperial Peptides and Domestic Peptides.  They do make up for it with their weekly email deals and coupon codes.  So, every week, I see which company has the best deal and it goes back and forth between these four companies with Enhanced getting at least an order per month from me.

I’ve found the other main advantage Enhanced Peptides has over the others is its payment processing options.  Just like the others, it uses an invoice system however, you have the ability to pay with credit card and an option at checkout to pay with an e-check using your routing and account numbers which really helps on the convenience.

Customer service is above average.  Quality and accuracy are spot on.  Enhanced Peptides has become one of the leading USA Peptide stores in a very short period of time. 


USA Peptides Companies Review
Scored 1-10    (1 bad - 5 average - 10 Best)

Top Peptides
Imperial Peptides
Domestic Peptides
Enhanced Peptides
Inventory/Selection
10
9
9
9
Price
10
9
9
8
Shipping speed
10
10
10
10
Packaging
10
10
10
10
USA Peptide company
10
10
10
10
Customer service
10
10
8
9
Discounts and Sales
10
8
8
9
Quality/Accuracy
10
10
10
10
Payment Options
9
9
7
9
Years in business
9
5
5
5
SCORE/100
98
90
86
90



In conclusion, overall Top Peptides leads the 4 USA Peptide online suppliers that we recommend.  They all have quality and consistent peptides for sale and are all USA based.   Each company is a trusted source to buy peptides and research chemicals and each of them has a unique and individual benefit to use.  I recommend going to each of their websites, bookmarking their website in your browser and sign up for their weekly newsletter.  Then whenever you need to buy peptides, find the best deal between the four online stores.  I guarantee you’ll never have to look anywhere else.

Growth Hormone Releasing Secretagogue (GHS) Peptides & Chemicals

Growth Hormone Secretagogues, also called GHSs, are synthetic chemicals, both in the form of peptides and non-peptides (research chemicals), that stimulate Growth Hormone release. 

To truly understand what this means, first let’s break apart this by each term. 
What is Growth Hormone?
Growth Hormone (GH), also known as somatotropin or Human Growth Hormone (HGH) in humans, is a peptide hormone that stimulates cell reproduction, growth and regeneration in humans and animals. 
Growth hormone production naturally decreases with age which has recently made it a popular medical treatment prescribed by doctors for growth hormone deficiency in adults to increase vitality.
What is a secretagogue?
A Secretagogue is a chemical or peptide that causes another chemical or hormone to be secreted. 
What is an agonist?
An agonist is a chemical or peptide that binds to a specific receptor and therefor activates the receptor to produce, or secrete, a chemical or hormone or a similar action.  Alternatively, an antagonist causes the opposite effect of an agonist.   For example, if an agonist causes the receptor to product more Growth Hormone, then an antagonist would cause the receptor to product less, or block the production of growth hormone.
Now that we understand these terms, let’s take another look at Growth Hormone Secretagogues (GHSs).
What are Growth Hormone Releasing Secretagogues (GHSs)
Growth Hormone Secretagogues (GHSs) are drugs, peptides or research chemicals, which induce the secretion of GH (growth hormone).  They include agonists of both the Growth Hormone Secretagogue Receptor (GHSR) such as GHRP-2, GHRP-6, Hexarelin and Ipamorelin which are all peptides and MK-677 which is a research chemical as well as agonists of the Growth Hormone Releasing Hormone Receptor (GHRHR) such as Sermorelin, Tesamorelin and CJC 1295 which are all peptides.  These agonist peptides also induce the secretion of IGF-1 and other hormones like prolactin and cortisol.  IGF-1 (Insulin -like Growth Factor 1) is a protein that regulates the concentration of free fatty acids and glucose.  You can buy peptides online and find igf-1 lr3 for sale at Top Peptides.

Growth Hormone Releasing Hormone Receptors
The GHRHR (Growth-hormone-releasing hormone receptor) is a G-protein-coupled receptor which binds growth hormone-releasing hormones together. It activates a Gs protein which causes intracellular signaling molecules called cAMPs via Adenylate cyclase pathways.
The function of this receptor is to release Growth Hormone.  Binding to the receptor leads to the release of additional growth hormone.
GHRHR Peptides
•    CJC-1295 DAC
•    Dumorelin
•    GHRH (somatorelin)
•    Rismorelin
•    Sermorelin
•    Tesamorelin

Growth hormone secretagogue receptors
Growth hormone secretagogue receptor(GHS-R) is also known as the ghrelin (the “hunger hormone” receptor.  It is a G protein-coupled receptor which binds growth hormone secretagogues (GHSs). The role of GHS-R is regulating both body weight and energy homeostasis.  Thiscombination has also made is a potential for abuse as a performance enhancing drug. 
The function of GHS-R’s is to release growth hormone by binding to the GHS-R1a which is located in the pituitary cells and stimulating the pituitary gland’s growth hormone (GH) secretion.

Ghrelin (GHS) receptor agonist Peptides
•    Alexamorelin
•    Hexarelin
•    Ghrelin (GHRL)
•    GHRP-1
•    GHRP-2
•    GHRP-3
•    GHRP-4
•    GHRP-5
•    GHRP-6
•    Ipamorelin

Ghrelin (GHS) receptor agonist non-peptides (research chemicals)
•    Adenosine
•    Anamorelin
•    Capromorelin
•    Ibutamoren
•    SM-130686

Where to buy Growth Hormone Releasing Secretagogue (GHS) Peptides

You can buy peptides and research chemicals online on research peptide websites for research purposes and never for human consumption.  I recommend Top Peptides.  They have a huge selection and great prices.  You can buy GHRP 6or any other Peptides for Sale there.

Wednesday, November 28, 2018

How to buy Clonazolam online?

Clonazolam is the research chemical which was introduced in the 1970 and is not available in the market. You can buy Clonazolam only for research purposes and never for human consumption. The drug is purchased by researchers who have plan to study and synthesize this potent drug. It is classified as a benzodiazepine, which is a chemical used to treat anxiety.
Some commonly prescribed benzodiazepines include Xanax and Valium.

Clonazolam is highly potent, so it can cause harm to your health.  This is the reason it is not allowed for human consumption and sold for research purposes only.Similar drug are used for the treatment of anxiety and depression.  The problem with these types of substances are a large number of patients prescribed these types of drugs abuse them by taking more than is prescribed. This can cause an accidental overdose, dizziness and many other health-related issues.
Pharmacology
The drugs onset takes approximately 45 minutes to one hour then the mind becomes anxiety free.  Its effect timeline depends on the amount however the effect in the bloodstream of test subjects lasted between 8 to 12 hours.  You can Buy Clonazolam USA online for your research from any certified research chemical supplier online.
Advantages and Disadvantages:
Like each medicine it also has some upsides as well as some downsides which are given as below:
Upsides: These are the positive effects that are proved by scientific researches and are quite helpful in medical sector suggested by doctors.
•    It has been known to help in reducing anxiety and depression symptoms in test subjects.
•    Lifts up your mood and helps in euphoria, brings sedation and a feeling of relaxation.
•    You will get aimproved and relaxed sleep.
•    Acts as a muscle relaxant.
Downsides: These are the negative effects that can occur when used in clinical trials on test subjects.
•    It causes dizziness and unconscious behavior and also causes amnesia.
•    Reduces coordination and become the reason of impairment of cognitive ornaments.

Bottom Line:

The drug is mostly used by scientists for research but similar benzodiazepines are now in the medical sector for treating many mental issues. Although the effects are good similar drugs are prescribed to be taken under the supervision of medical experts. You can purchase it for research online from a research chemical supplier in the USA. Hopefully this review is helpful in understanding the Clonazolam its good and bad potential effects and where to buy Clonazolam. Read it and make a secure purchase for your research projects.

Flubromazolam and its Uses

Flubromazolam is a derivative of the drug triazolam and is sold online as a research chemical. It has high potency value which makes it a highly potent drug and is considered similar toClonazolam and Pharmeceutical drugs like Xanax and Valium which are all benzodiazepines. These drugs have a higher risk of abuse which is one of the many reasons this drug should never be taken and only purchased for research. It is classified as a benzodiazepine.  Although it is not prescribed in the USA, it is sold in many countries when prescribed by a doctor.   Good examples are Switzerland and Sweden which allow its use due to its beneficial medical applications when supervised by a physician. You are only allowed to buy Flubromazolam USA for research within the United States.
How to Take It:
The drug takes 10 minutes for onset and sometimes takes up to one hour as reported by several research studies.
Effect and Side Effects:
Like all the drugs it has both the good and bad effects which are defined below:
Good Effects:
Benzodiazepines have been known to treat anxiety and depression.
Bad Effects:
These are the reactions and side effect that it can cause. These downsides are defined below:
It can increase confusion and cause inability in walking and talking, and prolonged sleep for periods which can last the whole day. The other effects include symptoms of sleep paralysis, increases anxiety, lack of control, and aches and sometimes blindness for a few times. Some reports showed less control over their brain because of high sedation and increase in anxiety.  The potential problem occurs when people use this dangerous drug for recreation instead of for research.  It can be an addictive and overdoses have been reported to cause death.
So, these are the side effects that it can cause due to consumption or overdose of this designer chemical. You can buy Flubromazolam USA online from any certified research chemical website. We recommend purchasing this drug only from stored located in the USA.
Conclusion:
Like all drugs which are used for research, the Flubromazolam is also suggested by doctors for the treatment of brain health-related issues. Online purchasesare a good way to buy these drugs or with the prescription of a medical doctor in areas that this substance is prescribed.  Buy Flubromazolam today, safely and securely online from a reputable USA store.  If you have any questions or concerns regarding your research project, please consult a physician or qualified scientist that is familiar with benzodiazepines and their effects and reactions. 

Monday, November 26, 2018

What are peptides and what do they do?

Peptides can either occur as natural or synthetic compound,and they are often identified by the linking of two or more amino acids in an amide formation. In regards to chemical bonding, peptides are known as covalent chemical compounds that are formed as a result of the combination of a carboxyl group from one amino acid, and an amino group of another amino acid.
You will often hear people refer to peptides as proteins and vice-versa. But there is a striking difference between proteins and peptides, their size.  The amino acids in peptides range from as small as two amino acids, to as much as fifty amino acids.  Proteins have over 50 amino acids.

What are the functions of Peptides
Peptides are classified based on how they function or how they are synthesized. Some examples of peptides classified according to function include; hormones, infectious USA peptides, neuro peptides and so on.
Below are some of the various functions of peptides in the body.
Transporters
One thing synonymous with most cells within the body is the fact that they have a protective membrane that prohibits substances (both needful and waste substances) from moving into the cell at will. This is where some peptides come to play a vital role as they act as transporting medium for some substances to gain access to the cell via the cell membrane. A good example is how glucose transporters help to convey glucose into muscles and other areas.
Enzymes
Enzymes are known as biological catalyst. Their major purpose is to alter the rate off chemical/metabolic reactions in the body. As it stands, most enzymes are peptides, and they found in various places in the body to help boost the rate of various chemical processes in the body. Such processes range from production of energy to digestion of food. The role a peptide has in the body, is determined by the size of the peptide along with the numbers of amino acid that makes up the peptide
Hormones
Hormones are biological messengers that use the blood stream as a transporting medium to convey information from one tissue to another. Peptide hormone and steroid hormone are the two common types of hormone. Some of the common peptide hormones include insulin and glucagon, both of play a role in blood glucose regulation, and also ghrelin and leptin, which help to regulate appetite

Structure
Another function of peptides is to act as structural elements within the body. This can be seen in the way actin peptide and myosin peptides, act as vital structural components of muscles. In addition, they also help with shaping and strengthening of bones in the body. The role peptides play in the muscles and bones of the body means, these two vital parts of the body can carry out their functions of providing structure to the body as well as, aiding with movement, and giving adequate protection to internal organs
In conclusion, Peptides are very vital to the daily functionality of the human body, and they play an essential role in several biological process of the body.  Synthetic Peptides like Oxytocin, Melanotan ii, IGF 1, TB500 and many others find their use in pharmaceutical and commercial industry, where they play significant roles. Some of the application of synthetic peptides can be seen in the creation of epitope-specific antibodies that combat pathogenic proteins, as well as identifying and characterizing proteins.  
The combined force of our naturally made peptides and our man-made peptides are to be determined.  We can only continue to create and research to find the next life changing peptide. 
If you or someone you know is considering using synthetic peptides in their next research project, we recommend buying your research chemicals and research peptides from Top Peptides.  Happy researching!




What is a Peptide?

Peptides are chains of amino acids joined together by amide bonds, also known as peptide bonds. A peptide is formed chemically as a result of a covalent bond which occurs between the carboxylic group of one amino acid and the amino group of another. The origin of the word peptide can be traced to a Greek word called Peptos, which means to digest. Naturally, peptides are crucial to life and occur in several numbers of form in the human and animal body. However, significant amounts of peptides have been synthesized, and also, many others are being produced daily. Peptide production has become extremely beneficial, both scientifically and financially, in the development of new drugs. Key health areas such as neurological activities, muscle growth, growth hormone deficiency, skin disorders are few of the many aspects where peptides have been found useful through research studies.

Where can you Buy Peptides for Research?

There are several places to buy peptides and research chemical online.  However, we recommend Top Peptides.  They have a huge selection of research peptides for sale because of their huge selection of research chemicals and research peptides.  We’ve also retested their chemicals and found that all of their products are extremely high quality and consistent.  If it says 50mg/ml then that’s what it is which is extremely important when using for research.
How are peptides made?

The production of peptides occurs both naturally in organism body and synthetically through peptide synthesis. Two kinds of peptides are created inside an organism; they are Ribosomal peptides and Non-ribosomal peptides. For synthetically produced peptides, they are formed through the solid-phase peptide synthesis method and the liquid-phase peptide synthesis technique to make sure that absolute purity is obtained. Many peptide manufacturers provide peptide based on length of sequence and Alterations.

The difference between a protein and a peptide

Peptides are usually differentiated from proteins, mainly based on size, with the standard of a peptide having 50 amino acids or less. A long and unbranched strand of amino acids that forms a peptide chain is known as a Polypeptide. Proteins are made up of one or more polypeptides in a way which makes them useful for biological purposes. Proteins can be found combined with another protein, different macromolecules such as DNA or RNA, a ligand or giant macromolecule structure. However, it is worthy to note that sometimes proteins can be referred to as peptides. For instance, thymosin beta-4 and insulin are mostly called peptides, but by definition they are proteins.
The number of Amino Acids in a peptide
The dipeptide is the shortest peptide known with only two amino acids. Peptides with three amino acids and four amino acids are referred to as tripeptide and tetrapeptide respectively. Peptides with eleven amino acids are referred to as undecapeptide, those with twelve amino acids are called dodecapeptide, and thirteen amino acids peptides are known as tridecapeptides and so on. Large peptides such as those with twenty amino acids are called icosapeptide while peptides with thirty amino acids and forty amino acids are referred to as tricontapeptide and tetracontapeptide respectively.
Different Types of Peptides

•    Ribosomal peptides are manufactured from the translation of mRNA, and mostly require proteolysis to become a matured structure. In higher organisms, ribosomal peptides function as hormones and signaling substances. The ribosome is the only peptide allowed to make use of the amino acid residues because of translational restrictions. Post-translation alterations are sometimes seen with these peptides such as disulfide formation or glycosylation. While such changes are mostly linear, other types of modifications also can place. Such cases can be seen when L-amino acids convert into D-amino acids.

•    Nonribosomal peptides are formed by peptide-specific enzymes rather than by ribosomes. Sometimes, they have a circular shape which can also occur in very complex cyclic forms. The linear arrangement of these peptides ismost common.

•    Milk peptidesare synthesized from milk proteins through theirbreakdownby digestive enzymes or via proteinases created by lactobacilli while the milk is being fermented.

•    Peptones are obtained from proteolytically digested meat or animal milk.

•    Peptide fragments – Peptide fragments are pieces of proteins which are usedin the calculation of data that has to do with source proteins. They are mostly formed as a result of enzymatic breakdown done on a controlled sample inside the laboratory. However, they can also be degraded naturally. AOD9604, Human Growth Hormone (HGH) Fragment 177-191 and IGF-1 DES are examples of Peptides Fragments and they all can be purchased at Top Peptides.

What is Flualprazolam?

Flualprazolamis a new synthetic research chemical that belongs to the chemical class of drugs called benzodiazepines.  The effects of this drug are similar to other benzodiazepines such as Alprasolam, or Xanax.  When administered, benzodiazepineshave been known to cause amnesia, anxiety suppression, muscle relation, disinhibition, hypnotic and anticonvulsant.  Flualprazolamis currently unscheduled and currently being researched for its effects in comparison to others in its class.  Since all information on this drug is relatively new, all information on this drug should not be entirely trusted until a consensus among medical professionals is reached.

This substance is a member of benzodiazepine class due to the fact that it has a 1, 4 diazepine ring joined to a substituted benzene ring. The Chlorine (Cl) group is attached right at the R7 position of this bicyclic structure. However, at R5 location of this structure, a fluorine-substituted phenyl ring is attached. This drug, Flualprazolam is fluorinated alprazolam, an attribute that gives it a slightly longer half-life and also makes it more potent compared to its parent compound.It’s highly recommended to avoid mixing any benzodiazepine with any other depressant substances like thienodiazepines, opiates, alcohol, barbiturates, and other GABAergic substances, most importantly heavy doses as this may lead to death.

Flualprazolam has strong potential for abuse and is highly addictive. In addition, the tolerance develops within a few days of consistent usage. Research has it that discontinuation of benzodiazepines can be very dangerous causes life-threatening effects in users who use this drug for a long time and quit abruptly or cold turkey. Gradual reduction of does is advised as sudden stoppage may cause unavoidable withdrawal symptoms such as seizure.  Always consult a physician regarding anything about this drug.  It can be a very dangerous substance which is why it is only sold for research purposes only and never for human consumption.

Flualprazolam Bioactivity
This substance exerts disinhibiting, sedative, muscle relaxing effects, hypnotic, anxiolytic, and memory suppressing effects when administered. Flualprazolam will likely exert its action through GABA receptors as it’s a benzodiazepine although the mechanism of its action is yet to be established. It displays some effects when bound to the receptor site of benzodiazepine, and it potentiates the effects of the neurotransmitter gamma amino butyric acid (GABA).

Expected Physical effects of flualprazolam

Flualprazolam expected physical effects include muscle relaxation, respiratory depression, sedation, temporary erectile dysfunction, physical euphoria, dizziness, loss of motor control, seizure suppression and an increase in libido. On administration, the paradoxical reactions will likely occur in people with mental disorders, recreational users, patients, and children on high-dose regimens such as aggression, increased seizure, violent behavior, suicidal behaviours, loss of impulse control, increased anxiety and irritability; however, the incidence rate is not more than 1 percent.

The cognitive effects exerted by flualprazolam include disinhibition, memory suppression, emotional depression, sleepiness, anxiety suppression, ego inflation, emotional suppression, compulsive redosing, thought deceleration, delusions of sobriety, etc.

Other names:
8-chloro-6-(2-fluorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine.